Nicotine and Mood: Does Vaping Help with Anxiety?
Jessica Tyson
11/07/2025 • 5 min readIn a world where stress and anxiety are increasingly common, with over a third of women and nearly a third of men in the UK reporting high levels of anxiety, it’s no surprise that many people turn to various habits and coping mechanisms to manage their mental health. For some, that includes vaping, often with the belief that nicotine can help them feel calmer or more focused.
But does vaping actually help with anxiety, or is that just a perception? In this article, we’ll explore how nicotine affects mood, what science says about its relationship with anxiety, and why some users report stress relief while others experience the opposite.
Understanding Nicotine’s Effect on the Brain
Nicotine is a stimulant found naturally in tobacco and used in a wide range of nicotine products, including e-liquids for vaping. Once inhaled or absorbed, nicotine rapidly enters the bloodstream and reaches the brain, where it binds to nicotinic acetylcholine receptors - specific sites that are part of our natural reward system.
This triggers the release of several crucial neurotransmitters, most notably dopamine, which is associated with pleasure and reward. It also increases levels of norepinephrine and serotonin, neurotransmitters linked to alertness, mood regulation, and stress response. These chemical changes can result in temporary feelings of calm, focus, or mild euphoria.
However, nicotine’s effects are inherently short-lived. The brain quickly adapts to nicotine's presence, and as its levels begin to drop, the body starts to experience withdrawal. This rapid decline can bring on a range of uncomfortable symptoms, including irritability, restlessness, difficulty concentrating, and increased anxiety. This cycle of temporary relief followed by withdrawal is a key mechanism behind nicotine dependence.
What Is Anxiety and How Is It Typically Managed?
Anxiety is more than just feeling worried, it's a significant mental health challenge that can profoundly impact daily life. It often presents as a persistent state of tension, dread, or fear that interferes with a person's ability to function normally. While occasional worry is a natural human experience, clinically diagnosed anxiety disorders, such as Generalised Anxiety Disorder (GAD), panic disorder, and social anxiety, involve symptoms that are chronic and debilitating.
Fortunately, several evidence-based and effective approaches are commonly employed to manage anxiety symptoms. These include:
- Cognitive behavioural therapy (CBT): A type of talk therapy that helps individuals identify and change unhelpful thinking patterns and behaviours that contribute to anxiety.
- Prescription medication: Often includes selective serotonin reuptake inhibitors (SSRIs) or benzodiazepines, prescribed by a doctor to help regulate brain chemistry.
- Mindfulness practices: Techniques such as meditation, yoga, and deep breathing exercises that help bring focus to the present moment and reduce physical tension and stress responses.
- Lifestyle changes: Fundamental shifts in daily habits, including a balanced diet, consistent quality sleep, and regular physical exercise, all of which significantly impact mental wellbeing.
Despite these proven methods, some people still turn to substances like caffeine, alcohol, or nicotine to self-manage symptoms. This approach often occurs without medical guidance and can inadvertently create new challenges or worsen existing ones.
The Science: Can Nicotine Help Relieve Anxiety Symptoms?
Scientific research presents a complex picture regarding nicotine's effects on anxiety, often appearing contradictory at first glance. On one hand, nicotine affects the brain’s chemistry by interacting with receptors that influence mood. It can stimulate the release of dopamine and serotonin - two key neurotransmitters involved in regulating how we feel. This biochemical activity may explain why some individuals report feeling calmer, more focused, or a temporary reduction in stress in the short term after using nicotine, especially if they are already feeling anxious or overwhelmed.
However, it's crucial to understand that this perceived calming effect is fleeting, and the long-term evidence tells a very different story. Despite these initial short-term effects, prolonged nicotine use is often linked to higher rates of anxiety and depression.
This apparent paradox is largely explained by the nicotine dependency cycle. Once the brain adapts to regular nicotine exposure, its absence (even brief periods, or the more prolonged nicotine absence overnight that leads to morning cravings) can trigger withdrawal symptoms that closely resemble anxiety, such as irritability, restlessness, and difficulty concentrating. What users often interpret as anxiety relief from vaping is, in fact, the temporary easing of these withdrawal symptoms. Nicotine isn't genuinely reducing anxiety; it's merely satisfying a craving its own presence created, only for the anxiety to return as nicotine levels drop. This is why people who are dependent on nicotine may struggle more with anxiety symptoms over time.
The good news is that quitting nicotine even after years of dependence can have a profoundly positive effect on mental wellbeing, and many people who successfully stop smoking often feel significantly less anxious in the long run, even if they used to think smoking helped them cope. This suggests that the act of smoking itself, and its associated dependency, was likely contributing to their anxiety all along, rather than truly relieving it.
For those looking to achieve this improved mental wellbeing by moving away from traditional smoking, transitioning to less harmful nicotine alternatives like vaping can be a significant step, especially when supported with expert advice.
Why Some People Turn to Vaping for Anxiety Relief
Despite the science, anecdotal reports often paint a more nuanced picture. Many vapers claim that vaping helps them unwind, concentrate, or take the edge off during stressful moments.
Some reasons people turn to vaping include:
- Stress relief after quitting smoking: For ex-smokers, vaping provides a less harmful alternative to traditional cigarettes. The familiar ritual of holding a device, the throat hit, and the exhalation of vapour can effectively mimic the smoking experience, helping to manage intense cravings and habitual urges associated with quitting cigarettes. This continuity offers a smoother transition and a sense of relief from the pressures of cessation.
- The ritual and sensory experience: Beyond its role in smoking cessation, the very act of vaping can be inherently soothing. The repetitive hand-to-mouth motion, the controlled inhale-exhale breathing pattern (which can mirror calming techniques like breathwork), and even the engagement of the senses through flavour choice and vapour production can all contribute to a feeling of calm, predictability, and momentary escape from stressors. Just like making tea or taking a walk, vaping can become a comforting routine that creates predictability and control - two things that can help with anxiety.
- Distraction: Taking a moment to vape can provide a deliberate break in a busy or stressful day. This brief pause offers a chance to step away from anxious thoughts, reset, and consciously focus on the act of breathing, functioning as a short mental escape.
However, it's important to distinguish between the comfort of the ritual and the pharmacological effects of nicotine. Not all relief felt from vaping is due to the substance itself; sometimes, the action is what matters.
Risks and Considerations
While vaping can serve as a vital tool for smoking cessation, it’s not without its own risks. Relying on nicotine as a primary coping mechanism for anxiety can introduce new challenges, such as:
- Nicotine dependence: Over time, the brain adapts to frequent nicotine exposure, leading to physical dependence. This means the body comes to rely on nicotine, resulting in cravings and withdrawal symptoms when levels drop.
- Mood swings: Fluctuating nicotine levels can cause irritability or worsen anxiety symptoms between vaping sessions, contributing to a sense of emotional instability.
- Masking underlying issues: Using nicotine to self-soothe can delay or prevent individuals from seeking more effective, evidence-based treatments for anxiety, such as therapy or medication. Vaping might temporarily alleviate symptoms, but it doesn't address the root causes of anxiety.
- A cycle of reliance: Treating vaping as an emotional crutch risks creating a reinforcing cycle where any relief is short-lived, and anxiety not only returns but can feel stronger without the nicotine, fostering an ongoing reliance rather than genuine coping abilities.
Expert Opinions
Most mental health professionals are cautious about endorsing nicotine for anxiety management. While they acknowledge that some people may feel temporary relief, the long-term drawbacks (especially related to addiction) often outweigh the short-term benefits.
Healthcare providers generally recommend:
- Speaking to a doctor or therapist before using nicotine to cope with anxiety.
- Exploring non-addictive tools and therapies that address root causes.
- Considering vaping only as a step away from smoking, not as a long-term solution.
Final Thoughts: Supporting Mental Wellbeing Beyond Nicotine
So, does vaping help with anxiety? The answer is nuanced. While some find temporary calm, especially when switching from smoking, nicotine can worsen anxiety over time as dependence builds. Scientific research suggests that any short-term relief is often outweighed by the longer-term effects nicotine has on mood regulation and stress response.
Ultimately, vaping shouldn't be viewed as a treatment for anxiety, but it can play a role in a broader journey toward better health, particularly for those moving away from cigarettes. If you're using nicotine and also struggling with anxiety, it's worth understanding both the potential benefits and limitations. While vaping might offer short-term comfort, longer-term emotional wellbeing is more likely to come from a combination of strategies, such as therapy, exercise, better sleep, and supportive routines.
If you're considering a switch or looking to reduce your nicotine use, having the right guidance can make a real difference. At FREESMO, we pride ourselves on helping people make informed, supported transitions, offering tailored advice and expert insights to make each step feel more manageable. If you're ready to take that step towards a smoke-free life with expert support, start your journey with us today.
Related articles
How Vaping Communities Support New Users Online
From forums and social groups to trusted brand websites, digital spaces have become lifelines for those starting their smoke-free journey.
The Real Cost of Tobacco Exposure: A Global Crisis with Local Consequences
Tobacco remains a top killer, particularly among men, and it continues to take a serious toll on communities across the world.
Why Do People Crave Nicotine in the Morning?
Discover why these cravings happen, what’s happening in your body and brain, and what you can do to reduce or manage them.
Will the Disposable Vape Ban Work?
We examines the potential impact of the disposable vape ban, separating facts from fears & exploring the real-world implications.
How to Transition from Smoking to Nicotine Pouches
Change doesn’t have to mean giving up nicotine entirely. More people switching to nicotine pouches - a smoke-free, discreet alternative.